“Experts are concerned about the spread of a new strain of bird flu that has already killed one woman in China,” BBC News reports. The new strain, which has evolved from an existing bird flu virus called H10N8…
“Experts are concerned about the spread of a new strain of bird flu that has already killed one woman in China,” BBC News reports.
The new strain, which has evolved from an existing bird flu virus called H10N8, has infected two people in China.
A case report in The Lancet medical journal warns that potential for a new pandemic “should not be underestimated”.
Their genetic tests of the strain suggests it has adapted to infect humans more easily.
That said, experts suggest there is currently no cause for alarm. There is no evidence that the new strain can pass between humans. Also, the woman who died of the new strain had pre-existing health conditions, including heart disease and high blood pressure, which may have made her more vulnerable to the effects of infection.
It is likely that the Chinese authorities will closely monitor the situation to assess whether there is a potential for a new pandemic to emerge.
There are many types of bird flu, most of which are harmless to humans. However, two types have caused serious concern in recent years. These are the H5N1 (since 1997) and H7N9 (since 2013) viruses.
Although these viruses don't infect people easily and are usually not transmitted from human to human, hundreds of people have been infected around the world, leading to a number of deaths.
The H10N8 virus discussed in the current news has never been reported in a human before.
Bird flu is in the news again because scientists have identified a new strain of the H10N8 virus. Their article, published in the peer reviewed medical journal The Lancet, reports on a 73 year old woman from Nanchang City in China, who was admitted to hospital in November last year with fever and severe pneumonia.
The woman had been exposed to chickens in a live poultry market a few days previously. Despite antibiotic and antiviral treatment she deteriorated rapidly, developed multiple organ failure and died nine days after the onset of symptoms.
The researchers took swab samples from the patient’s windpipe seven and nine days after onset of her illness. Laboratory tests showed they were positive for a new strain of the H10N8 virus, which they have called JX346.
The researchers carried out further detailed genetic analysis of the samples. They found that all the genes of the JX346 virus were of avian origin and that six genes share a common history with the avian H9N2 viruses, also found in poultry in China.
They suggest that JX346 might originate from “multiple reassortments” between different avian flu viruses. In other words, various strains are interacting with each other with the net result of a new strain being produced.
They also found the new strain had a gene mutation that is thought to be associated with increased virulence, meaning the virus might more easily infect people and the disease could be more severe.
The source of the patient’s infection is unknown. She had visited a live poultry market a few days before the onset of illness, however no H19N8 virus was found in samples collected from the poultry site since the patient’s visit.
Any reports of bird flu viruses being found in humans is a cause for concern since at present, there are no vaccines against them and the human population has no pre-existing immunity to them. For example, by July 2013, the H5N1 virus had infected 633 people, 377 of whom had died, with Indonesia, Egypt and Vietnam experiencing most cases and fatalities. Since March 2013, there have been reports of people being infected with the H7N9 virus in eastern China. By July 2013, there were 134 confirmed cases and 43 deaths.
However, people who have had bird flu generally developed the virus after coming into close and prolonged contact with infected birds. Millions of birds have been killed during outbreaks to prevent the disease spreading and being passed on to people.
For both the above viruses, there have been some reports of limited human to human transmission, usually as a result of very close contact between family members.
It should be noted that the patient who died in China had several chronic illnesses and a weakened immune system which may have made her particularly susceptible to the virus. There is no evidence that the new strain had transmitted to close contacts of the patient.
For people in the UK the risk of catching bird flu is very low. There are a number of things you can do to reduce your risk when you visit areas where outbreaks have been reported, such as:
There are no restrictions on travel to countries that have been or are currently affected by bird flu.