Treating Stevens-Johnson syndrome

If Stevens-Johnson syndrome is suspected, you or your child will be immediately referred to hospital for treatment. Without treatment, the symptoms can become very severe and be life-threatening.

Severe cases of Stevens-Johnson syndrome may need to be treated in an intensive care unit (ICU) or burns unit.

The first step is to stop taking any medications that may be causing Stevens-Johnson syndrome. However, it can sometimes be difficult to determine which medication is causing it, so stopping all non-essential medications may be recommended.

Treatment for relief of symptoms while in hospital may include:

  • strong painkillers to help ease the pain of any raw areas of skin
  • cool, moist compresses held against the skin dead skin may be gently removed and a sterile dressing placed over the affected area
  • regularly applying a plain (unscented) moisturiser to the skin
  • replacement fluids you may receive fluids and nutrition through a tube thats passed through your nose and into your stomach (a nasogastric tube)
  • mouthwashes containing anaesthetic and/or antiseptic to temporarily numb your mouth and make swallowing easier
  • a short course of corticosteroid tablets (topical corticosteroids) to control skin inflammation (only on specialist advice)
  • antibiotics if blood poisoning (sepsis) is suspected
  • eyedrops or eye ointment for eye-related symptoms

Once the cause of Stevens-Johnson syndrome has been identified and successfully treated (in the case of an infection), or stopped (in the case of medication), the skin reaction will stop. New skin may start to grow after a few days.

However, the length of time it takes to recover from Stevens-Johnson syndrome will depend on how severe it is, and it can sometimes take many weeks or months to fully recover.

If the cause was an adverse reaction to medication, you'll need to avoid that medication and possibly other similar medications for the rest of your life. The doctor treating you will be able to advise you further about this.

Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dec 2018