Complicationsof Stevens-Johnson syndrome

As Stevens-Johnson syndrome severely affects the skin and mucous membranes, it can cause a number of complications. These include:

  • skin changes when your skin grows back it may be uneven in colour; less commonly, scarring may occur
  • secondary skin infection (cellulitis) which can lead to further, serious problems such as blood poisoning (sepsis)
  • problems with internal organs organs can become inflamed for example, the lungs (pneumonia) , heart (myocarditis), kidneys (nephritis) or liver (hepatitis) ; the oesophagus may also become narrowed and scarred (oesophageal stricture)
  • eye problems the rash can cause problems with your eyes which, in mild cases, may be irritation and dry eyes , or in severe cases may result in corneal ulceration, uveitis (inflammation of the uvea, which is the middle layer of the eye) and, possibly, blindness

Problems with the sexual organs, such as vaginal stenosis (narrowing of the vagina caused by a build-up of scar tissue), and scarring of the penis, is also a possible complication of Stevens-Johnson syndrome.

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Medically Reviewed by a doctor on 21 Dec 2018