Symptoms of Stevens-Johnson syndrome

Skin pain is the most common symptom of Stevens-Johnson syndrome.

Flu-like symptoms are also usually present during the initial stages, and may include:

  • feeling generally unwell
  • a high temperature (fever) of 38C (100.4F) or above
  • a headache
  • joint pain
  • a cough

After a few days a rash appears, which may look like a target darker in the middle and lighter around the outside (see below). The rash isn't usually itchy, and spreads over a number of hours or days. Large blisters then develop on the skin, which after bursting leave painful sores.

Facial swelling and swollen lips covered in crusty sores are common features of Stevens-Johnson syndrome. The mucous membranes inside your mouth, throat, eyes and genital tract may also become blistered and ulcerated. This can make swallowing painful and lead to serious problems such as dehydration .

The surface of the eyes can also sometimes be affected, which if not treated quickly can cause corneal ulcers and vision problems (see Complications of Stevens-Johnson syndrome , below).

Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dec 2018