Hereditary neuropathy with pressure palsies (HNPP)
There's currently no cure for HNPP, but some of the symptoms can be treated, and lifestyle changes can make a huge difference.
Ifyou can feel anywarning signs (such as tingling),stop what you're doing to try to preventfurther damage tothe nerve.
It's wise to avoid:
Make a note of the sorts of activities that trigger symptoms and change the way you do them next time for example, use a machine or tool to do the work, or get someone to help you.
An occupational therapist can advise on ways you can best carry out day-to-day activities.
Physiotherapy isnot usually needed.A damaged nerve needs time to repair itself, so if you have muscle weakness, carry on using the limb just enough to keep the blood flowing to it to help it heal, but go easyand don't push it.
If you're overweight, now may be a good time to lose the weight if the disease gets worse, you may find it difficult to be active.
People with foot drop or wrist drop may benefit from an ankle-foot orthosis or wrist splint, which can be worn at night.
Protective pads for the elbows and knees may prevent the nerves from being aggravated.
Afoam pad on top of the mattress may also lessen pressure on the affected nerve.
If you're suffering from nerve pain, some antidepressants and anti-seizure drugs may help.
This helps scientists look for better ways to prevent and treat this condition. You can opt out of the register at any time.
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Hereditary neuropathy with pressure palsies (HNPP) is an inherited nerve disorder that typically causes numbness, tingling and muscle weakness.
HNPPranges in severity some people get no symptoms at all or find it a minor nuisance, while others are so badly affected they can't even move the affected limb. Most people with HNPP have attacks o
We needtwo PMP22 genes, one from each parent, for the normal development of the peripheral nerves.These genesprovide instructions for the creation of PMP22 protein, whichmakes uptheprotective outer la
A diagnosis of HNPP is based on symptoms(such asrecurrent loss of sensation in one particular area), evidence of a family history and electrical nerve tests. A genetic test will confirm the diagnosis.
There's currently no cure for HNPP, but some of the symptoms can be treated, and lifestyle changes can make a huge difference. Lifestyle advice Ifyou can feel anywarning signs (such as tingling),sto
HNPP.org HNPP UK Hereditary Neuropathy Foundation CMT UK