Ehlers-Danlos syndrome

How EDS is inherited

EDS can be inherited, but in some cases it occurs by chance in someone without a family history of the condition.

The two main ways that EDS is inherited are:

autosomal dominant inheritance (hypermobile, classical and vascular EDS) the faulty gene that causes EDS is passed on by one parent and there's a 50% risk of each of theirchildren developing the condition
autosomal recessive inheritance (kyphoscoliotic EDS) the faulty gene is inherited from both parents and there's a 25% risk of each of their children developing the condition

A person with EDS can only pass on the same type of EDS to their children. For example,the childrenof someone with hypermobile EDS can't inherit vascular EDS.

The severity of the condition can vary withinthe samefamily.

Medically Reviewed by a doctor on 21 Dec 2018

Articles for ehlers-danlos syndrome

Introduction

Ehlers-Danlos syndrome (EDS) is the name for a group of rare inherited conditions that affect connective tissue. Find out about the symptoms, causes and treatments.

Main types of EDS

EDS-hypermobile type is the most common type of EDS. Rarer types include classical EDS, vascular EDS and kyphoscoliotic EDS. EDS-hypermobile type EDS-hypermobile type (EDS-HT), also known as hypermo

Getting medical advice

See your GP if you have several troublesome symptoms of EDS. You don't usually need to worry if you only have a few symptoms and they're not causing any problems. Joint hypermobility, for example, is

Living withEDS

There's no specific treatment for EDS, but with support and advice it's possible to manage many of the symptoms. Adapting your activities It's important to be careful about activities that put a lot

How EDS is inherited

EDS can be inherited, but in some cases it occurs by chance in someone without a family history of the condition. The two main ways that EDS is inherited are: autosomal dominant inheritance (hyper

Information about you

If you have EDS, your clinical team will pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS). This helps scientists look for better ways

More information

The following websites provide moreinformation, advice and support forpeople with EDS and their families: Ehlers-Danlos Support UK you can also call their free helpline on0800 907 8518, find local

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