Thrombophilia is where the blood has an increased tendency to form clots.

It's not a condition or a disorder itself, and is sometimes associated with blood clots (venous thromboses) that are caused by genetic changes (mutations).

If you have thrombophilia, you're more likely to develop a blood clot in one of the large veins in your leg. This is known as deep vein thrombosis (DVT).

It's important to be aware of the signs of a DVT, such as unexplained pain, swelling or tenderness in your leg (usually in your calf). See your GP as soon as possible if you have these symptoms (see below).

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Medically Reviewed by a doctor on 21 Jun 2016