Pancreas transplant
Apancreas transplant is a major operation. As withall types of surgery, there is a risk of complications.
Some complications can occur soon after the procedure, while others may develop months, or even years, later.
Some of themain risks associated with a pancreastransplant are described below.
One of the most common complications of apancreas transplant is rejection of the donor pancreas. This is where the immune system recognises the transplantedpancreas as foreign and attacks it.
Rejection usually occurs in the days, weeks or months after the transplant, although it can sometimes happen years later.
Immunosuppressant medication can reduce the risk of this happening, but can't always prevent it completely.
Symptoms of rejection can include:
Contact your GP or transplant team as soon as possible if you have these symptoms. Rejection can usually be treated by increasing your dose of immunosuppressant medication.
The immunosuppressant medications you need to take to prevent rejection can have a number of significant side effects.
These can include:
Speak to your transplant team if you experience any troublesome side effects. Don't stop taking your medication without getting medical advice first.
Immunosuppressant medication will weaken your immune system and make you more vulnerable to infection.
While taking the medication, it's a good idea to:
To help prevent infection, you may be given antibiotics , antifungal medicine or antiviralmedicationto take for the first few weeks or monthsafter your transplant.
Blood clots can sometimes form in the blood vessels that supply the new pancreas, which can stop it working properly.
The risk of this happening is highest in the days after the operation, so you will be closely monitored in hospital to check for any signs of a blood clot.
You'll alsobe given blood-thinning medication to reduce the chances of a clot forming.
If a blood clot does develop in the new pancreas, you'll usually need another operation to remove it.
Blood clots can also form in other blood vessels after surgery, such as those in your legs (deep vein thrombosis) or supplying your lungs (pulmonary embolism) , but taking blood-thinning medication should help prevent this.
Pancreatitis is swelling (inflammation) of the pancreas, and is common in the first few days after surgery.
It can occur as a result of storing the donor pancreas on ice in preparation for the transplant.
Symptoms of pancreatitis include:
Pancreatitis should pass within a few days.However,sometimes tubes may need to be placed in your tummy to drain any excess fluid off the donor pancreas, and in a few cases it may be necessary to remove it.
Find out why pancreas transplants are carried out, what they involve, and the potential risks.
Find out about when a pancreas transplant may be considered, how you will be assessed to determine if one is suitable, and who might not be able to have one.
You will be referred for an assessment if a pancreas transplant is thought to be a suitable option.
Find out what happens during a pancreas transplant and islet transplant.
Find out what happens after a pancreas transplant, including how long you may need to stay in hospital and the ongoing care you'll need.
Find out about the possible complications of a pancreas transplant, including rejection of the donor pancreas and side effects from immunosuppressant medication.
Ivy Ashworth-Crees, who used to have diabetes, talks about how much better her life is since her double kidney and pancreas transplant.