Interactions with other medicines

Some NSAIDs can react unpredictably with other medications. This can affect how well either medicineworks and increase the risk of side effects.

It's particularly important to getmedical advice before taking an NSAID if you're already taking:

  • another NSAID
  • low-dose aspirin or warfarin medicines used to prevent blood clots
  • ciclosporin a medicine used to treat autoimmune conditions such as arthritis or ulcerative colitis
  • diuretics medicinessometimes used to treat high blood pressure
  • lithium a medicine used to treat bipolar disorder and severe depression
  • methotrexate a medicine used to treat rheumatoid arthritis
  • a type of antidepressant medicine called a selective serotonin reuptake inhibitor (SSRI)

If you're not sure whether a medication you're taking can be taken at the same time as an NSAID, check the leaflet that comes with it, or ask a pharmacist or doctor for advice.

Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dec 2018