Nail patella syndrome
The main signs and symptoms of nail patella syndrome are listed below.
Someonewith the condition may not have all these symptoms andsome symptoms maybe more severe than others.
Some of theproblems will be obvious from birth, but others may not become apparent until later on.
Nearly all people with nail patella syndrome will have abnormal or missing nails, which is usually apparent at birth.
The base of each nail is often triangular, rather than a curved crescent shape, and the nails themselves may be underdeveloped, discoloured, split, ridged or pitted.
Thumbnails are the most severely affected, and the nails are less severely affected from the index finger towards the little finger. Toenails are generally less affected than fingernails.
Other areas of the body that can be affected include the bones and joints, kidneys and eyes.
Common features include:
It has also been suggested that people with nail patella syndrome may be more likely to have attention deficit hyperactivity disorder (ADHD) or depression , although more research is needed to confirm this.
Nail patella syndrome is a rare genetic condition that can involve problems with the nails, bones, kidneys and eyes. It's thought to affect about 1 in 50,000 people.
The main signs and symptoms of nail patella syndrome are listed below. Someonewith the condition may not have all these symptoms andsome symptoms maybe more severe than others. Some of theproblems w
Most people with nail patella syndrome will have inherited a defective version of a gene called LMX1B from one of their parents. This gene is important in the development of a baby's limbs, nails, kid