Mastocytosis causesa wide range of symptoms, whichcan vary depending on the type of mastocytosis you have.
Skin lesionsare a characteristic of cutaneous mastocytosis. Types of lesions known to occur in cutaneous mastocytosis include:
Lesions usually develop on the trunk rather than the head, neck and limbs.
The lesions, known as urticaria pigmentosa,are usually yellow-tan to reddish-brown in colour, and can range from 1mm to several centimetres in size.
The number of lesions that develop on the skin can vary widely. For example, it's possible for only one lesion to develop, or more than 1,000.
Stroking the affectedareas of skin can make it swollen, itchy and red over the lesion.
If you have systemic mastocytosis, you may develop sudden episodes of symptoms that last for around 15-30 minutes. However, many people don't have any problems.
The most common symptoms experienced during an episode are:
Less common symptoms during anepisode include:
Once the episode has passed you'll probably feel sluggish (lethargic) for several hours.
The episodesare caused by the mast cells suddenly releasing excessive amounts of histamine, usually after you're exposed to certain triggers.
Triggers known to causeepisodes include:
Abnormal mast cells in your bone marrow and organs can also cause related symptoms, including:
In more severe cases of mastocytosis, the following symptoms may occur:
Some people with severe symptoms experience a sudden fall inblood pressure during an attack.
Low blood pressure (hypotension) can trigger a number of associated symptoms, such as:
If you have systemic mastocytosis or extensive cutaneous mastocytosis, your risk of a severe allergic reaction (anaphylaxis) is increased.
It's important to look out for the initial symptoms of anaphylaxis, which include:
Dial 999immediately and ask for anambulance if you think you or someone else is experiencing symptoms of anaphylaxis.
Read about mastocytosis, a rare condition caused by an excess number of mast cells gathering in the body's tissues.
Read about the symptoms of mastocytosis, which can vary depending on the type of mastocytosis you have.
Read about treatment options for mastocytosis, which depend on which type you have and how severe your symptoms are.