Leukaemia, acute myeloid
If you have acute myeloid leukaemia (AML), you may experience a number of complications. These can be caused by the condition itself, although they can also occur as a side effect of treatment.
Some of the main complications associated with AML are outlined below.
Having a weakened immune system being immunocompromised is a common complication of AML.
Even if your blood is restored to normal working order with treatment, many of the medications that are used to treatAML can temporarily weaken your immune system.
This means you're more vulnerable to developing an infection, and any infection you develop could be more serious than usual. Complications arising from infection are the leading cause of death in people with AML. However, if treated early, nearly all infections respond to appropriate treatment.
Therefore, you may be advised to:
Report any possible symptoms of an infectionto yourtreatment unit immediately because prompt treatment may be needed to prevent complications.
Symptoms of an infection caninclude:
If you have AML, you'll bleed and bruise more easily due to the low levels of platelets (clot-forming cells) in your blood. Bleeding may also be excessive.
People with advanced AML are morevulnerable to excessive bleeding inside their body, which is the second most common cause of death in people with the condition.
Serious bleeding can occur:
All these types of haemorrhage should be regarded as medical emergencies. Dial 999 immediately and ask for an ambulance if you think a haemorrhage is occurring.
Many of the treatments that are used to treat AML can cause infertility .This is often temporary, but in some cases can be permanent.
People particularly at risk of permanent infertility are those who have received high doses of chemotherapy and radiotherapy in preparation for a bone marrow or stem cell transplant .
Your treatment team can give a good estimation of the risk of infertility in your specific circumstances.
It may be possible to guard against any risk of infertility before you begin your treatment. For example, men can have their sperm samples stored. Similarly, women can have eggs orfertilised embryos stored, which can then be placed back into their womb, following treatment.
However, as AML is an aggressive condition that develops rapidly, there may not always be time to do this before treatment needs to start.
Read about acute myeloid leukaemia (AML) - an aggressive cancer of the myeloid cells. Information about signs and symptoms, causes, diagnosis and treatment.
Read about the symptoms of acute myeloid leukaemia (AML), which include pale skin, tiredness, breathlessness, fever, sweating, weight loss and frequent infections.
Read about what causes acute myeloid leukaemia (AML), plus risk factors, such as previous cancer treatment, smoking, and having certain blood or genetic disorders.
Read about how acute myeloid leukaemia (AML) is diagnosed using blood tests, a bone marrow biopsy and other specialised tests.
Find out how acute myeloid leukaemia (AML) is treated using a combination of radiotherapy, chemotherapy and, in some cases, a bone marrow transplant.
Read about the possible complications of acute myeloid leukaemia (AML), including a weakened immune system, haemorrhage (bleeding) and infertility.