Cholesterol Lowering Medicines Statins
When statins may be used
Source: NHS
In this topic (4)
Statins may be recommended if you have cardiovascular disease (CVD) or have a high risk of developing it in the next 10 years.
Cardiovascular disease (CVD)
(CVD) is a general term that describes a disease of the heart or blood vessels, often caused by high cholesterol . It's the most common cause of death in the UK.
The main types of CVD are:
- coronary heart disease when the blood supply to the heart becomes restrictedas a result of the hardening and narrowing of the arteries ( atherosclerosis )
- angina sharp chest pain caused by coronary heart disease
- heart attacks when the supply of blood to the heart is suddenly blocked
- strokes and transient ischaemic attacks (TIAs) when the supply of blood to the brain becomes blocked or disrupted
- peripheral arterial disease (PAD) whena build-up of fatty deposits in the arteries restricts blood supply to the limbs
Statins can't cure these conditions, but they canhelp prevent them from getting worse or recurring in people who have been diagnosed with them.
They can alsoreduce the chance of these conditions developing in the first place in people at risk (see below).
Statins are usually used in combination with lifestyle measures such as:
- eating a healthy diet low in saturated fat
- exercising regularly
- stopping smoking
- moderating your alcohol consumption
People at risk ofCVD
If you don't have any form of CVD, statins may still be recommended if you're thought to be at a high risk of developing the condition in the future.
The current recommendation is that you should be offered statins if:
- there's at least a 1 in 10 chance of you developing CVD at some point in the next 10 years
- lifestyle measures, such as exercising regularly and eating a healthy diet, haven't reduced this risk
Your GP may recommend carrying out a formal assessment of your CVD risk if they think you may be at an increased risk of CVD, based on your personal and family medical history.
For this formal assessment,your GPor practice nurse will use special CVD risk assessment computer software that takes into account factors such as:
- your age
- your gender
- your ethnic group, as some have an increased risk of CVD
- your weight and height
- if you smoke or have previously smoked
- if you have a family history of CVD
- your blood pressure
- your blood cholesterol levels
- if you have certain long-term conditions such as diabetes , chronic kidney disease , rheumatoid arthritis and atrial fibrillation (a heart condition that causes an irregular and often abnormally fast heart rate)
This is an inherited condition caused by a genetic fault that leadstohigh cholesterol levels, even in people who have a generally healthy lifestyle.
Articles for Cholesterol Lowering Medicines Statins
Cautions and interactions with statins
Statins should not be taken if you have severe liver disease or blood tests suggest that your liver may not be working properly.
Introduction
Statins are a group of medicines that can help lower the level of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol is often referred to as "bad cholesterol", and statins reduce the production of it inside the liver.
Main side effects of statins
Like all medications, statins can cause side effects. However, most people tolerate them well and don't experience any problems.
When statins may be used
Statins may be recommended if you have cardiovascular disease (CVD) or have a high risk of developing it in the next 10 years.