Narinder Kaur-Logue has an aggressive form of relapsing remitting multiple sclerosis (MS). She experiences debilitating fatigue on a daily basis and has regular relapses.
Earlier this year, she began having a monthly infusion of the disease-modifying drug (DMD) Tysabri.
"When I was first offered Tysabri, I didnt want it. Id heard about people who had died on the trial and didnt want to put my life at risk. When my doctor explained how isolated those cases were, and that the treatment had finished trials and had been approved for treating aggressive forms of MS, I decided I would give it a go."
Narinder had previously taken Copaxone and AvonexDMDs that are self-injected.
"I had lots of side affects with Avonex and I hated the daily injections with Copaxone. I felt like I was stabbing myself and sometimes had to ask my husband to do it for me.The monthly infusions for Tysabri are painless and straightforward, and I no longer have the stress of bad injection site bruises."
Narinders MS symptoms include fatigue, mobility and vision problems. "Im unable to work because of my fatigue," she explains. "I tend to get errands and exercise done in the morning, and then come midday my body starts to shut down, fatigue sets in and I cant do anything other than rest; its like flicking a switch".
Tysabri has been known to cause the life-threatening virus progressive multifocal leukoencephalopathy (PML), but risk of developing this is small. Potential side effects of the treatment can include infections, headaches, dizziness, vomiting, nausea, liver damage and infusion reactions.Narinder started receiving the infusions in January and hasnt experienced any side effects so far (eight months later).
She said: "I can notice a difference in myself and it seems to be keeping some symptoms at bay. My balance has improved; I dont wobble as much when I stand after sitting and I now have the confidence to wash my hair without someone in the house. I have more energy too. I danced at a party recently something I havent done in a long time."
"Im lucky that Ive been able to access Tysabri I know of others that have had to campaign for months.Tysabri wont work for everyone; it only treats aggressive forms of relapsing remitting MS and some people may develop side effects or not like the idea of the two-hour hospital infusions once a month, but its working well for me at the moment."
Multiple sclerosis (MS) is a condition which can affect the brain and/or spinal cord, causing a wide range of potential symptoms, including problems with vision, arm or leg movement, sensation or balance.
Read about the main symptoms of multiple sclerosis (MS), including fatigue, unusual sensations, difficulties with movement and vision problems.
Exactly why someone develops multiple sclerosis (MS) isn't known. It's not caused by anything you've done and it's not clear whether it can be prevented.
It can be hard to tell whether your symptoms might be caused by multiple sclerosis (MS) at first, as some of the symptoms can be quite vague or similar to other conditions.
There's currently no cure for multiple sclerosis (MS), but it's possible to treat the symptoms with medications and other treatments.
You may have to adapt your daily life if you're diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
Jo was diagnosed with multiple sclerosis after the birth of her son. She explains how it affects her body, her ability to move around and her family life.
Narinder Kaur-Logue has an aggressive form of relapsing remitting multiple sclerosis. She experiences debilitating fatigue on a daily basis and has regular relapses.
Leonie Martin, age 45, has relapsing-remitting multiple sclerosis.She explains how she learnt to manage her symptoms.