How GA1 is inherited

The geneticcause (mutation)of GA1 is passed on by the parents, who usually dont have any symptoms of the condition.

The way this mutation is passed on is known as autosomal recessive inheritance. This means a baby needs to receive two copies of the mutated gene to develop the condition one from their mother and one from their father. If the baby only receives one mutated gene, theyll just be a carrier of GA1.

If youre a carrier of theaffected gene and you have a baby with a partner whos also a carrier, your baby has:

  • a 25% chance of developing the condition
  • a 50% chance of being a carrier of GA1
  • a 25% chance of receiving a pair of normal genes

Although its not possible to prevent GA1, its important to let your midwife and doctor know if you have a family history of the condition. Any further children you have can be tested for the condition as soon as possible and given appropriate treatment.

You may also wish to consider genetic counselling for support, information and advice about genetic conditions.

Content supplied by the NHS Website

Medically Reviewed by a doctor on 21 Dez 2018